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Laboratory Bioreactor EDF-5.4

EDF-5.4 is a glass bioreactor with working volume till 4.5 l (total volume 6.2 l, inside diameter 150mm). The bioreactor is mounted on stainless steel pipeline legs.

It is foreseen for the cultivation of bacterial cultures, filamentous fungi, yeast, microalgae, mammalian cell cultures and stem cells. Depending on the applied microbial culture it is possible to adapt the configuration of the bioreactor in a corresponding way.

EDF-5.4 includes the following main parts and features:

  • Completed bioreactor vessel with a novel upper magnetic drive. The range of mixer rotation speed is 40 - 1000 rpm;
  • Bioprocess controller BIO-4 controls pH, pO2, temperature, antifoam level, solution level, mixer revolutions in the Basic configuration, as well as additional parameters and operations according to the customer request. pO2 cascade control and time dependent feeding profiles are also included in the Basic configuration;
  • Stainless steel "monoblock" construction, which contains the bioprocess controller BIO-4, the thermostat, peristaltic pumps, power control parts, gas supply and mixing (air, O2) units;
  • Thermoregulation is carried out by circulation of thermostated water trough the jacket, which covers the bottom of the bioreactor;
  • 4 free configurable peristaltic pumps;
  • The possibility of wireless control using smartphones (iPhone and others) and tablet computers (iPad and others);
  • Accessories for upper lid (needles, sparger, chemostat tube, ports for sensors, condenser with outlet filter and valve);
  • Two rotameters for air and O2, inlet and exhaust air filters;
  • A valve and a program module for O2 enrichment process;
  • Temperature, foam and level sensors;
  • A sterilizable pH sensor from Finesse (PHS-EFP-K8-325) or Mettler-Toledo (405-DPAS-SC-K85/325) with stainless steel protection covering and fittings;
  • A sterilizable pO2 sensor from Finesse (DOS-OFF-D4-325) or Mettler Toledo (Inpro 6820/12/320) with fittings;
  • Autoclavable sampling device in the bottom of the vessel;
  • A frame for titration bottles (3);
  • Other standard accessories to ensure full functionality of the fermentation process (bottles for titration liquids, tubes, spare parts etc.).

Optionally:

  • A special mixer for mycelial and other shear sensitive microorganisms;
  • A gas mixing system (O2, N2, CO2);
  • A PC SCADA program for process data monitoring, data archiving and control. A special USB dongle key for seamless remote access to the SCADA system can be supplied.
  • Application and integration of additional sensors (redox, O2 and CO2 in exhaust gas, gas flow rates, optical density and other);
  • Automatic feeding control, using a supplement program, based on MATLAB;
  • Customer specialised solutions for adapting to different microorganisms cultivation tasks.